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Sex Differences in Dose Escalation and Overdose Death during Chronic Opioid Therapy: A Population-Based Cohort Study

BACKGROUND: The use of opioids for noncancer pain is widespread, and more than 16,000 die of opioid-related causes in the United States annually. The patients at greatest risk of death are those receiving high doses of opioids. Whether sex influences the risk of dose escalation or opioid-related mor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kaplovitch, Eric, Gomes, Tara, Camacho, Ximena, Dhalla, Irfan A., Mamdani, Muhammad M., Juurlink, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546305/
https://ncbi.nlm.nih.gov/pubmed/26291716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134550
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