Adenovirus-mediated chronic “hyper-resistinemia” leads to in vivo insulin resistance in normal rats
We investigated the chronic in vivo effect of resistin on insulin sensitivity and glucose metabolism by overexpressing resistin protein in male Wistar rats using intravenous administration of an adenovirus encoding mouse resistin. After 7 days of elevated resistin levels at a supraphysiological conc...
Uloženo v:
| Vydáno v: | J Clin Invest |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI20785 |
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