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Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein

In a number of neurological diseases including Parkinson’s disease (PD), α‑synuclein is aberrantly folded, forming abnormal oligomers, and amyloid fibrils within nerve cells. Strong evidence exists for the toxicity of increased production and aggregation of α-synuclein in vivo. The toxicity of α-syn...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Roberts, Hazel L., Brown, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496673/
https://ncbi.nlm.nih.gov/pubmed/25816357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5020282
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