Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [(123)I]-CLINME, a New SPECT Tracer for the Translocator Protein

The high affinity translocator protein (TSPO) ligand 6-chloro-2-(4′-iodophenyl)-3-(N,N-methylethyl)imidazo[1,2-a]pyridine-3-acetamide (CLINME) was radiolabelled with iodine-123 and assessed for its sensitivity for the TSPO in rodents. Moreover neuroinflammatory changes on a unilateral excitotoxic le...

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Publicado no:Dis Markers
Main Authors: Mattner, F., Quinlivan, M., Greguric, I., Pham, T., Liu, X., Jackson, T., Berghofer, P., Fookes, C. J. R., Dikic, B., Gregoire, M.-C., Dolle, F., Katsifis, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496498/
https://ncbi.nlm.nih.gov/pubmed/26199457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/729698
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