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Synthesis, radiosynthesis and in vivo evaluation of [(123)I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine as a selective tracer for imaging the dopamine transporter
Dopamine transporter (DAT) neuroimaging is a useful tool in Parkinson’s disease diagnosis, staging and follow-up providing information on the integrity of the dopaminergic neurotransmitter system in vivo. 4-(2-(Bis(4-fluorophenyl)-methoxy)ethyl)-1-(4-iodobenzyl)piperidine (7) has nanomolar affinity...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739387/ https://ncbi.nlm.nih.gov/pubmed/19746191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.1603 |
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