Delphinidin sensitizes prostate cancer cells to TRAIL-induced apoptosis, by inducing DR5 and causing caspase-mediated HDAC3 cleavage

TRAIL can induce apoptosis in some cancer cells and is an immune effector in the surveillance and elimination of developing tumors. Yes, some cancers are resistant to TRAIL. Delphinidin, a polyphenolic compound contained in brightly colored fruits and vegetables, has anti-inflammatory, anti-oxidant,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ko, Hyeonseok, Jeong, Mi-Hyeon, Jeon, Hyelin, Sung, Gi-Jun, So, Youngsin, Kim, InKi, Son, JaeKyoung, Lee, Sang-wook, Yoon, Ho-Geun, Choi, Kyung-Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496411/
https://ncbi.nlm.nih.gov/pubmed/25991668
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