TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma

Tumor necrosis factor α (TNFα) and other members of the TNF family affect adipose tissue metabolism and contribute to the obesity-related inflammation of adipose tissue. Here, we sought to identify the effects of TRAIL (TNF-related apoptosis-inducing ligand) on fat cell biology. TRAIL-receptor 2 (TR...

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Detalhes bibliográficos
Main Authors: Keuper, M, Wernstedt Asterholm, I, Scherer, P E, Westhoff, M-A, Möller, P, Debatin, K-M, Strauss, G, Wabitsch, M, Fischer-Posovszky, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563999/
https://ncbi.nlm.nih.gov/pubmed/23348588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.212
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