TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors

Tumor necrosis factor-α (TNFα) and other ligands of the TNF superfamily are potent regulators of adipose tissue metabolism and play a crucial role in the obesity-induced inflammation of adipose tissue. Adipose tissue expression levels of TRAIL (TNF-related apoptosis-inducing ligand) and its receptor...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zoller, Verena, Funcke, Jan-Bernd, Keuper, Michaela, Abd El Hay, Muad, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133965/
https://ncbi.nlm.nih.gov/pubmed/27735943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.286
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