TERT promoter mutations and telomere length in adult malignant gliomas and recurrences

In this report on 303 gliomas we show the highest frequency of TERT promoter mutations in gliobastomas (80%) followed by oligodendrogliomas (70%) and astrocytomas (39%). We observed positive association between TERT promoter and IDH mutations in oligodendroglial tumors (OR = 26.3; 95% CI 2.5–250.2)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Heidenreich, Barbara, Rachakonda, P. Sivaramakrishna, Hosen, Ismail, Volz, Florian, Hemminki, Kari, Weyerbrock, Astrid, Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496380/
https://ncbi.nlm.nih.gov/pubmed/25797251
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