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TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas

BACKGROUND: Activating somatic mutations in the promoter region of the telomerase reverse transcriptase gene (TERT) have been detected in several cancers. In this study we investigated the TERT promoter mutations and their impact on patient survival in World Health Organization grade IV glioblastoma...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Simon, Matthias, Hosen, Ismail, Gousias, Konstantinos, Rachakonda, Sivaramakrishna, Heidenreich, Barbara, Gessi, Marco, Schramm, Johannes, Hemminki, Kari, Waha, Andreas, Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483052/
https://ncbi.nlm.nih.gov/pubmed/25140036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou158
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