Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution

Rapid neurotransmitter release depends on the Ca(2+)-sensor Synaptotagmin-1 and the SNARE complex formed by synaptobrevin, syntaxin-1 and SNAP-25. How Synaptotagmin-1 triggers release remains unclear, in part because elucidating high-resolution structures of Synaptotagmin-1-SNARE complexes has been...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Brewer, Kyle D., Bacaj, Taulant, Cavalli, Andrea, Camilloni, Carlo, Swarbrick, James D., Liu, Jin, Zhou, Amy, Zhou, Peng, Barlow, Nicholas, Xu, Junjie, Seven, Alpay B., Prinslow, Eric A., Voleti, Rashmi, Häussinger, Daniel, Bonvin, Alexandre M.J.J., Tomchick, Diana R., Vendruscolo, Michele, Graham, Bim, Südhof, Thomas C., Rizo, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496268/
https://ncbi.nlm.nih.gov/pubmed/26030874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3035
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