The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration

The unfolded protein response (UPR) occurs following the accumulation of unfolded proteins in the endoplasmic reticulum (ER) and orchestrates an intricate balance between its prosurvival and apoptotic arms to restore cellular homeostasis and integrity. However, in certain neurodegenerative diseases,...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Varadarajan, S, Breda, C, Smalley, J L, Butterworth, M, Farrow, S N, Giorgini, F, Cohen, G M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495362/
https://ncbi.nlm.nih.gov/pubmed/25656655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.1
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