TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation

REST/NRSF is a transcriptional repressor of neuronal genes that has been implicated in development and cancer. In epithelial tissues, REST acts as a tumor suppressor and in breast cancer, loss of REST is associated with disease recurrence and poor prognosis. Here, we identify TSPYL2 (also known as C...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Epping, M T, Lunardi, A, Nachmani, D, Castillo-Martin, M, Thin, T H, Cordon-Cardo, C, Pandolfi, P P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495358/
https://ncbi.nlm.nih.gov/pubmed/25613376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.226
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