Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF

Neuroinflammation is associated with synapse dysfunction and cognitive decline in patients and animal models. One candidate for translating the inflammatory stress into structural and functional changes in neural networks is the transcriptional repressor RE1-silencing transcription factor (REST) tha...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Buffolo, Federica, Petrosino, Valentina, Albini, Martina, Moschetta, Matteo, Carlini, Federico, Floss, Thomas, Kerlero de Rosbo, Nicole, Cesca, Fabrizia, Rocchi, Anna, Uccelli, Antonio, Benfenati, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884694/
https://ncbi.nlm.nih.gov/pubmed/33589593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03465-6
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