Angiotensin II suppresses osteoblastic differentiation and mineralized nodule formation via AT(1) receptor in ROS17/2.8 cells

INTRODUCTION: Angiotensin II (Ang II) not only regulates systemic blood pressure through a vasoconstrictive effect, but also promotes bone resorption. We recently reported that Ang II (10(–6) M) stimulated the production of matrix metalloproteinases via the AT(1) receptor in osteoblastic ROS17/2.8 c...

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Publicado en:Arch Med Sci
Autores principales: Nakai, Kumiko, Kawato, Takayuki, Morita, Toyoko, Yamazaki, Yoji, Tanaka, Hideki, Tonogi, Morio, Oki, Hidero, Maeno, Masao
Formato: Artigo
Lenguaje:Inglês
Publicado: Termedia Publishing House 2015
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495158/
https://ncbi.nlm.nih.gov/pubmed/26170858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2015.52369
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