RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

Derailed endolysosomal trafficking is emerging as a widespread feature of aggressive neoplasms. However, the oncogenic signals that alter membrane homeostasis and their specific contribution to cancer progression remain unclear. Understanding the upstream drivers and downstream regulators of aberran...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Alonso-Curbelo, Direna, Osterloh, Lisa, Cañón, Estela, Calvo, Tonantzin G., Martínez-Herranz, Raúl, Karras, Panagiotis, Martínez, Sonia, Riveiro-Falkenbach, Erica, Romero, Pablo-Ortiz, Rodríguez-Peralto, José Luis, Pastor, Joaquín, Soengas, María S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Priority Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494909/
https://ncbi.nlm.nih.gov/pubmed/26008978
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