Drug Dosing in Obese Children: A Systematic Review of Current Pharmacokinetic Data

IMPORTANCE: Obesity affects nearly one sixth of U.S. children and results in alterations to body composition and physiology that can affect drug disposition, possibly leading to therapeutic failure or toxicity. The depth of available literature regarding obesity’s effect on drug safety, pharmacokine...

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Опубликовано в: :JAMA Pediatr
Главные авторы: Harskamp-van Ginkel, Margreet W., Hill, Kevin D., Becker, Kristian, Testoni, Daniela, Cohen-Wolkowiez, Michael, Gonzalez, Daniel, Barrett, Jeffrey S., Benjamin, Daniel K., Siegel, David A., Banks, Patricia, Watt, Kevin M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494887/
https://ncbi.nlm.nih.gov/pubmed/25961828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapediatrics.2015.132
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