Drug Dosing in Obese Children: A Systematic Review of Current Pharmacokinetic Data

IMPORTANCE: Obesity affects nearly one sixth of U.S. children and results in alterations to body composition and physiology that can affect drug disposition, possibly leading to therapeutic failure or toxicity. The depth of available literature regarding obesity’s effect on drug safety, pharmacokine...

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Detalhes bibliográficos
Publicado no:JAMA Pediatr
Main Authors: Harskamp-van Ginkel, Margreet W., Hill, Kevin D., Becker, Kristian, Testoni, Daniela, Cohen-Wolkowiez, Michael, Gonzalez, Daniel, Barrett, Jeffrey S., Benjamin, Daniel K., Siegel, David A., Banks, Patricia, Watt, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494887/
https://ncbi.nlm.nih.gov/pubmed/25961828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapediatrics.2015.132
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