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Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
Zinc is abundant in the central nervous system and regulates pain, but the underlying mechanisms are unknown. In vitro studies have shown that extracellular zinc modulates a plethora of signaling membrane proteins, including NMDA receptors containing the NR2A subunit, which display exquisite zinc se...
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| 出版年: | Nat Neurosci |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494785/ https://ncbi.nlm.nih.gov/pubmed/21725314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2844 |
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