Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro

Lower back pain is a common concern, and 40% of all cases involve the degeneration of the intervertebral disc (IVD). However, the excessive apoptosis of disc cells plays an important role in IVD degeneration, particularly in the nucleus pulposus (NP). Thus, anti-apoptotic gene therapy to attenuate o...

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: MA, XUEXIAO, LIN, YAZHOU, YANG, KUN, YUE, BIN, XIANG, HONGFEI, CHEN, BOHUA
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494593/
https://ncbi.nlm.nih.gov/pubmed/26017192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2225
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