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Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro

Lower back pain is a common concern, and 40% of all cases involve the degeneration of the intervertebral disc (IVD). However, the excessive apoptosis of disc cells plays an important role in IVD degeneration, particularly in the nucleus pulposus (NP). Thus, anti-apoptotic gene therapy to attenuate o...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: MA, XUEXIAO, LIN, YAZHOU, YANG, KUN, YUE, BIN, XIANG, HONGFEI, CHEN, BOHUA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494593/
https://ncbi.nlm.nih.gov/pubmed/26017192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2225
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