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Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer’s Disease Like Tau Aggregation

Intracellular neurofibrillary tangles and extracellular senile plaques are potential targets for active and passive immunotherapies. In this study we used the transgenic mouse model P301S for active immunizations with peptide vaccines composed of a double phosphorylated tau neoepitope (pSer202/pThr2...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Richter, Monique, Mewes, Agneta, Fritsch, Manuela, Krügel, Ute, Hoffmann, Ralf, Singer, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494214/
https://ncbi.nlm.nih.gov/pubmed/26344748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines2030601
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