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What Does It Take to Evolve an Enhancer? A Simulation-Based Study of Factors Influencing the Emergence of Combinatorial Regulation

There is widespread interest today in understanding enhancers, which are regulatory elements typically harboring several transcription factor binding sites and mediating the combinatorial effect of transcription factors on gene expression. The evolution of enhancers poses interesting unanswered ques...

詳細記述

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書誌詳細
出版年:Genome Biol Evol
主要な著者: Duque, Thyago, Sinha, Saurabh
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494070/
https://ncbi.nlm.nih.gov/pubmed/25956793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv080
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