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What Does It Take to Evolve an Enhancer? A Simulation-Based Study of Factors Influencing the Emergence of Combinatorial Regulation

There is widespread interest today in understanding enhancers, which are regulatory elements typically harboring several transcription factor binding sites and mediating the combinatorial effect of transcription factors on gene expression. The evolution of enhancers poses interesting unanswered ques...

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Bibliografiska uppgifter
I publikationen:Genome Biol Evol
Huvudupphovsmän: Duque, Thyago, Sinha, Saurabh
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494070/
https://ncbi.nlm.nih.gov/pubmed/25956793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv080
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