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The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium
Mutations in RPGRIP1L result in severe human diseases called ciliopathies. To unravel the molecular function of RPGRIP1L, we analyzed Rpgrip1l(−/−) mouse embryos, which display a ciliopathy phenotype and die, at the latest, around birth. In these embryos, cilia-mediated signaling was severely distur...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494006/ https://ncbi.nlm.nih.gov/pubmed/26150391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408060 |
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