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Control of Hedgehog Signalling by the Cilia-Regulated Proteasome

The Hedgehog signalling pathway is evolutionarily highly conserved and essential for embryonic development of invertebrates and vertebrates. Consequently, impaired Hedgehog signalling results in very severe human diseases, ranging from holoprosencephaly to Pallister-Hall syndrome. Due to this great...

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Detalhes bibliográficos
Publicado no:J Dev Biol
Main Authors: Gerhardt, Christoph, Wiegering, Antonia, Leu, Tristan, Rüther, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831775/
https://ncbi.nlm.nih.gov/pubmed/29615591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jdb4030027
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