Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Although Schwann cell myelin breakdown is the universal outcome of a remarkably wide range of conditions that cause disease or injury to peripheral nerves, the cellular and molecular mechanisms that make Schwann cell–mediated myelin digestion possible have not been established. We report that Schwan...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Gomez-Sanchez, Jose A., Carty, Lucy, Iruarrizaga-Lejarreta, Marta, Palomo-Irigoyen, Marta, Varela-Rey, Marta, Griffith, Megan, Hantke, Janina, Macias-Camara, Nuria, Azkargorta, Mikel, Aurrekoetxea, Igor, De Juan, Virginia Gutiérrez, Jefferies, Harold B.J., Aspichueta, Patricia, Elortza, Félix, Aransay, Ana M., Martínez-Chantar, María L., Baas, Frank, Mato, José M., Mirsky, Rhona, Woodhoo, Ashwin, Jessen, Kristján R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494002/
https://ncbi.nlm.nih.gov/pubmed/26150392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503019
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