S-adenosylmethionine levels regulate the Schwann cell DNA methylome

Axonal myelination is essential for rapid saltatory impulse conduction in the nervous system, and malformation or destruction of myelin sheaths leads to motor and sensory disabilities. DNA methylation is an essential epigenetic modification during mammalian development, yet its role in myelination r...

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Detalhes bibliográficos
Main Authors: Varela-Rey, Marta, Iruarrizaga-Lejarreta, Marta, Lozano, Juan José, Aransay, Ana María, Fernandez, Agustín F., Lavin, José Luis, Mósen-Ansorena, David, Berdasco, María, Turmaine, Marc, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Esteller, Manel, Mirsky, Rhona, Jessen, Kristján R., Fraga, Mario F., Martínez-Chantar, María L., Mato, José M., Woodhoo, Ashwin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960855/
https://ncbi.nlm.nih.gov/pubmed/24607226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.037
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