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Methanocarba ring as a ribose modification in ligands of G protein-coupled purine and pyrimidine receptors: synthetic approaches

Adenosine receptors (ARs) and P2Y receptors for purine and pyrimidine nucleotides have widespread distribution and regulate countless physiological processes. Various synthetic ligands are in clinical trials for treatment of inflammatory diseases, pain, cancer, thrombosis, ischemia, and other condit...

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Bibliografische gegevens
Gepubliceerd in:Medchemcomm
Hoofdauteurs: Tosh, Dilip K., Jacobson, Kenneth A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493925/
https://ncbi.nlm.nih.gov/pubmed/26161251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20348K
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