VISA - Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

BACKGROUND: Analyzing the integration profile of retroviral vectors is a vital step in determining their potential genotoxic effects and developing safer vectors for therapeutic use. Identifying retroviral vector integration sites is also important for retroviral mutagenesis screens. RESULTS: We dev...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Hocum, Jonah D., Battrell, Logan R., Maynard, Ryan, Adair, Jennifer E., Beard, Brian C., Rawlings, David J., Kiem, Hans-Peter, Miller, Daniel G., Trobridge, Grant D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493804/
https://ncbi.nlm.nih.gov/pubmed/26150117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0653-6
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