Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination

DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the Smc5–Smc6 complex is recruited to DSBs de novo to support their repair by homologous reco...

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Bibliografiset tiedot
Julkaisussa:Nat Cell Biol
Päätekijät: De Piccoli, Giacomo, Cortes-Ledesma, Felipe, Ira, Gregory, Torres-Rosell, Jordi, Uhle, Stefan, Farmer, Sarah, Hwang, Ji-Young, Machin, Felix, Ceschia, Audrey, McAleenan, Alexandra, Cordon-Preciado, Violeta, Clemente-Blanco, Andrés, Vilella-Mitjana, Felip, Ullal, Pranav, Jarmuz, Adam, Leitao, Beatriz, Bressan, Debra, Dotiwala, Farokh, Papusha, Alma, Zhao, Xiaolan, Myung, Kyungjae, Haber, James E., Aguilera, Andrés, Aragón, Luis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493748/
https://ncbi.nlm.nih.gov/pubmed/16892052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1466
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