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Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay

The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sharma, Vasundhara, Jordan, Jennifer J., Ciribilli, Yari, Resnick, Michael A., Bisio, Alessandra, Inga, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493129/
https://ncbi.nlm.nih.gov/pubmed/26147604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130170
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