Evolution of p53 Transactivation Specificity through the Lens of a Yeast-Based Functional Assay

Co-evolution of transcription factors (TFs) with their respective cis-regulatory network enhances functional diversity in the course of evolution. We present a new approach to investigate transactivation capacity of sequence-specific TFs in evolutionary studies. Saccharomyces cerevisiae was used as...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Lion, Mattia, Raimondi, Ivan, Donati, Stefano, Jousson, Olivier, Ciribilli, Yari, Inga, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323202/
https://ncbi.nlm.nih.gov/pubmed/25668429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116177
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