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Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display

We have developed a peptide display platform based on VLPs of the RNA bacteriophage MS2 that combines the high immunogenicity of VLP display with affinity selection capabilities. Random peptides can be displayed on the VLP surface by genetically inserting sequences into a surface-exposed loop of the...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Crossey, Erin, Frietze, Kathryn, Narum, David L., Peabody, David S., Chackerian, Bryce
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493041/
https://ncbi.nlm.nih.gov/pubmed/26147502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132560
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