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Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display

We have developed a peptide display platform based on VLPs of the RNA bacteriophage MS2 that combines the high immunogenicity of VLP display with affinity selection capabilities. Random peptides can be displayed on the VLP surface by genetically inserting sequences into a surface-exposed loop of the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Crossey, Erin, Frietze, Kathryn, Narum, David L., Peabody, David S., Chackerian, Bryce
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493041/
https://ncbi.nlm.nih.gov/pubmed/26147502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132560
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