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Immunogenic Display of Diverse Peptides, Including a Broadly Cross-Type Neutralizing Human Papillomavirus L2 epitope, on Virus-like Particles of the RNA Bacteriophage PP7

The immunogenicity of an antigen can be dramatically increased by displaying it in a dense, multivalent context, such as on the surface of a virus or virus-like particle (VLP). Here we describe a highly versatile VLP platform for peptide display based on VLPs of the RNA bacteriophage PP7. We show th...

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Detalhes bibliográficos
Main Authors: Caldeira, Jerri do Carmo, Medford, Alexander, Kines, Rhonda C., Lino, Christopher A., Schiller, John T., Chackerian, Bryce, Peabody, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881612/
https://ncbi.nlm.nih.gov/pubmed/20434554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.04.049
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