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Microprocessor mediates transcriptional termination in long noncoding microRNA genes
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding gene...
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Publicado no: | Nat Struct Mol Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492989/ https://ncbi.nlm.nih.gov/pubmed/25730776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2982 |
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