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Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are important regulators of cell fate, yet little is known about mechanisms controlling lncRNA expression. Here we show that transcription is quantitatively different for lncRNAs and mRNAs—as revealed by deficiency of Dicer (Dcr), a key RNase that generates microRNAs (m...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509563/ https://ncbi.nlm.nih.gov/pubmed/24929436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2842 |
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