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Primary microRNA transcripts are processed co-transcriptionally
microRNAs (miRNAs) are generated from long primary (pri-) RNA polymerase II (Pol II)–derived transcripts by two RNase III processing reactions: Drosha cleavage of nuclear pri-miRNAs and Dicer cleavage of cytoplasmic pre-miRNAs. Here we show that Drosha cleavage occurs during transcription acting on...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952270/ https://ncbi.nlm.nih.gov/pubmed/19172742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1475 |
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