Fibrinolysis Shutdown Phenotype Masks Changes in Rodent Coagulation in Tissue Injury versus Hemorrhagic Shock

INTRODUCTION: Systemic hyperfibrinolysis (accelerated clot degradation) and fibrinolysis shutdown (impaired clot degradation) are associated with increased mortality compared to physiologic fibrinolysis following trauma. Animal models have not reproduced these changes. We hypothesize rodents have a...

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Veröffentlicht in:Surgery
Hauptverfasser: Moore, Hunter B, Moore, Ernest E, Lawson, Peter, Gonzalez, Eduardo, Fragoso, Miguel, Morton, Alex P, Gamboni, Fabia, Chapman, Michael P, Sauaia, Angela, Banerjee, Anirban, Silliman, Christopher C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492895/
https://ncbi.nlm.nih.gov/pubmed/25979440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.04.008
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