TRO40303, a mitochondrial-targeted cytoprotective compound, provides protection in hepatitis models

TRO40303 is cytoprotective compound that was shown to reduce infarct size in preclinical models of myocardial infarction. It targets mitochondria, delays mitochondrial permeability transition pore (mPTP) opening and reduces oxidative stress in cardiomyocytes submitted to ischemia/reperfusion in vitr...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Schaller, Sophie, Michaud, Magali, Latyszenok, Virginie, Robert, Fabrice, Hocine, Mélanie, Arnoux, Thomas, Gabriac, Mélanie, Codoul, Hélène, Bourhane, Ahmed, de Bellefois, Isabel Clémançon, Afxantidis, Jean, Pruss, Rebecca M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492760/
https://ncbi.nlm.nih.gov/pubmed/26236486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.144
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