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Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease

In Huntington disease (HD), there is increasing evidence for a link between mutant huntingtin expression, mitochondrial dysfunction, energetic deficits and neurodegeneration but the precise nature, causes and order of these events remain to be determined. In this work, our objective was to evaluate...

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Detalhes bibliográficos
Main Authors: Gouarné, Caroline, Tardif, Gwenaëlle, Tracz, Jennifer, Latyszenok, Virginie, Michaud, Magali, Clemens, Laura Emily, Yu-Taeger, Libo, Nguyen, Huu Phuc, Bordet, Thierry, Pruss, Rebecca M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841140/
https://ncbi.nlm.nih.gov/pubmed/24303051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081528
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