Pharmacological properties of acid N-thiazolylamide FFA2 agonists

FFA2 is a receptor for short-chain fatty acids. Propionate (C3) and 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide (4-CMTB), the prototypical synthetic FFA2 agonist, evoke calcium mobilization in neutrophils and inhibit lipolysis in adipocytes via this G-protein-coupled receptor. 4-CMTB c...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Brown, Andrew J, Tsoulou, Christina, Ward, Emma, Gower, Elaine, Bhudia, Nisha, Chowdhury, Forhad, Dean, Tony W, Faucher, Nicolas, Gangar, Akanksha, Dowell, Simon J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492757/
https://ncbi.nlm.nih.gov/pubmed/26236484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.141
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