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(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

Most hematopoietic stem cell gene therapy studies require host conditioning to allow for efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment-related toxicities are especially relevant for the treatment of nonmalignant blood disorders, such as hemoglobinopathies a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther
Hauptverfasser: Burtner, Christopher R., Chandrasekaran, Devikha, Santos, Erlinda B., Beard, Brian C., Adair, Jennifer E., Hamlin, Donald K., Wilbur, D. Scott, Sandmaier, Brenda M., Kiem, Hans-Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492596/
https://ncbi.nlm.nih.gov/pubmed/25919226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.021
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