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Fine-Tuning of the Actin Cytoskeleton and Cell Adhesion During Drosophila Development by the Unconventional Guanine Nucleotide Exchange Factors Myoblast City and Sponge

The evolutionarily conserved Dock proteins function as unconventional guanine nucleotide exchange factors (GEFs). Upon binding to engulfment and cell motility (ELMO) proteins, Dock–ELMO complexes activate the Rho family of small GTPases to mediate a diverse array of biological processes, including c...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Biersmith, Bridget, Wang, Zong-Heng, Geisbrecht, Erika R.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492379/
https://ncbi.nlm.nih.gov/pubmed/25908317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.177063
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