A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases

BACKGROUND. RAF inhibitors are an effective therapy for patients with BRAF-mutant melanoma and brain metastasis. Efficacy data are derived from clinical studies enriched with physiologically fit patients; therefore, it is of interest to assess the real-world experience of vemurafenib in this populat...

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Veröffentlicht in:Oncologist
Hauptverfasser: Harding, James J., Catalanotti, Federica, Munhoz, Rodrigo R., Cheng, Donavan T., Yaqubie, Amin, Kelly, Nicole, McDermott, Gregory C., Kersellius, Romona, Merghoub, Taha, Lacouture, Mario E., Carvajal, Richard D., Panageas, Katherine S., Berger, Michael F., Rosen, Neal, Solit, David B., Chapman, Paul B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2015
Schlagworte:
Melanoma and Cutaneous Malignancies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492223/
https://ncbi.nlm.nih.gov/pubmed/25956405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0012
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