A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases

BACKGROUND. RAF inhibitors are an effective therapy for patients with BRAF-mutant melanoma and brain metastasis. Efficacy data are derived from clinical studies enriched with physiologically fit patients; therefore, it is of interest to assess the real-world experience of vemurafenib in this populat...

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Vydáno v:Oncologist
Hlavní autoři: Harding, James J., Catalanotti, Federica, Munhoz, Rodrigo R., Cheng, Donavan T., Yaqubie, Amin, Kelly, Nicole, McDermott, Gregory C., Kersellius, Romona, Merghoub, Taha, Lacouture, Mario E., Carvajal, Richard D., Panageas, Katherine S., Berger, Michael F., Rosen, Neal, Solit, David B., Chapman, Paul B.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2015
Témata:
Melanoma and Cutaneous Malignancies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492223/
https://ncbi.nlm.nih.gov/pubmed/25956405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0012
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