A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases

BACKGROUND. RAF inhibitors are an effective therapy for patients with BRAF-mutant melanoma and brain metastasis. Efficacy data are derived from clinical studies enriched with physiologically fit patients; therefore, it is of interest to assess the real-world experience of vemurafenib in this populat...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Harding, James J., Catalanotti, Federica, Munhoz, Rodrigo R., Cheng, Donavan T., Yaqubie, Amin, Kelly, Nicole, McDermott, Gregory C., Kersellius, Romona, Merghoub, Taha, Lacouture, Mario E., Carvajal, Richard D., Panageas, Katherine S., Berger, Michael F., Rosen, Neal, Solit, David B., Chapman, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
Melanoma and Cutaneous Malignancies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492223/
https://ncbi.nlm.nih.gov/pubmed/25956405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0012
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