A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases

BACKGROUND. RAF inhibitors are an effective therapy for patients with BRAF-mutant melanoma and brain metastasis. Efficacy data are derived from clinical studies enriched with physiologically fit patients; therefore, it is of interest to assess the real-world experience of vemurafenib in this populat...

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Bibliographic Details
Published in:Oncologist
Main Authors: Harding, James J., Catalanotti, Federica, Munhoz, Rodrigo R., Cheng, Donavan T., Yaqubie, Amin, Kelly, Nicole, McDermott, Gregory C., Kersellius, Romona, Merghoub, Taha, Lacouture, Mario E., Carvajal, Richard D., Panageas, Katherine S., Berger, Michael F., Rosen, Neal, Solit, David B., Chapman, Paul B.
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2015
Subjects:
Melanoma and Cutaneous Malignancies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492223/
https://ncbi.nlm.nih.gov/pubmed/25956405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0012
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