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Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data

BACKGROUND: A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. They aid the formation of loops in the DNA that function to isolate different structural domains. A recent experimental technique, Hi-C, provides a method for determining the frequency of s...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Saberi, Saeed, Farré, Pau, Cuvier, Olivier, Emberly, Eldon
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492175/
https://ncbi.nlm.nih.gov/pubmed/26001583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0584-2
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