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Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data

BACKGROUND: A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. They aid the formation of loops in the DNA that function to isolate different structural domains. A recent experimental technique, Hi-C, provides a method for determining the frequency of s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Saberi, Saeed, Farré, Pau, Cuvier, Olivier, Emberly, Eldon
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492175/
https://ncbi.nlm.nih.gov/pubmed/26001583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0584-2
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