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Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data

BACKGROUND: A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. They aid the formation of loops in the DNA that function to isolate different structural domains. A recent experimental technique, Hi-C, provides a method for determining the frequency of s...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Saberi, Saeed, Farré, Pau, Cuvier, Olivier, Emberly, Eldon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492175/
https://ncbi.nlm.nih.gov/pubmed/26001583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0584-2
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