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Reduction of Urease Activity by Interaction with the Flap Covering the Active Site

With the increasing appreciation for the human microbiome coupled with the global rise of antibiotic resistant organisms, it is imperative that new methods be developed to specifically target pathogens. To that end, a novel computational approach was devised to identify compounds that reduce the act...

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Vydáno v:J Chem Inf Model
Hlavní autoři: Macomber, Lee, Minkara, Mona S., Hausinger, Robert P., Merz, Kenneth M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491936/
https://ncbi.nlm.nih.gov/pubmed/25594724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500562t
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